Marios C. Panayi

This study shows that the D3R antagonist VK4-116 improves behavioral flexibility in rats with a history of cocaine use during abstinence.

The paper shows that cocaine seeking and taking are oppositely regulated by dopamine in rats, with cue-evoked dopamine changes linked to relapse and escalated consumption.

This study shows that GluA1 dysfunction leads to impaired short-term habituation, resulting in a hyper-dopaminergic phenotype in the nucleus accumbens, which may contribute to aberrant salience in schizophrenia.

This study investigates the role of D1 receptors in the nucleus accumbens core in regulating reward-seeking behavior during Go/No-Go tasks in rats.

This study examines how 5-HT2C receptor perturbation affects instrumental vigour and restraint in rats, finding that systemic activation boosts performance and reduces restraint, while dopamine enhances restraint and action initiation.

This study shows that the retrosplenial cortex is necessary for both spatial and non-spatial latent learning in mice, specifically during the preconditioning phase.

The paper shows that intraneuronal chloride levels increase with wakefulness, reducing synaptic inhibition and affecting cortical function, and that targeting chloride can restore performance in tired states.

This study identifies distinct anatomical projection patterns into different subregions of the rat OFC along both anterior-posterior and medial-lateral axes.

This study investigates how rodent lateral OFC lesions affect Pavlovian cue-outcome learning, finding that pre-training lesions enhance acquisition while post-training lesions impair it.

This study investigates the role of the rodent lateral orbitofrontal cortex in outcome devaluation and reversal learning, finding dissociable effects between subregions and task types.