Author

Stephen B. Melville

Virginia TechORCID 0000-0002-0116-4280Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Anne M. BrowniD· 1 shared Collette Camper· 1 shared Crysten BlabyiD· 1 shared Ian K. HickliniD· 1 shared Julia M. Tani· 1 shared Richard F. HelmiD· 1 shared Samantha Dempsey· 1 shared Sarah E. Kivimaki· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperMicrobiology

Anne M. BrownORCID

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1 paper

Recent·Most cited

Type IV pili-associated secretion of a biofilm matrix protein from Clostridium perfringens that forms intermolecular isopeptide bonds

Sarah E. Kivimaki, Samantha Dempsey, Collette Camper, Julia M. Tani, William Keith Ray, Ian K. Hicklin, Richard F. Helm, Crysten Blaby, Anne M. Brown, Stephen B. Melville

This study identifies a biofilm matrix protein, BsaC, secreted by Clostridium perfringens via type IV pili, and shows BsaA forms intermolecular isopeptide bonds to enhance biofilm fiber strength.

Molecular Microbiology · Sep 22, 2025Peer-reviewedMicrobiology