Richard F. Helm

This study demonstrates that bioengineered gastric mucus from human gastric organoids closely mimics native human gastric mucus in structure, function, and proteomic profile.

This study identifies a biofilm matrix protein, BsaC, secreted by Clostridium perfringens via type IV pili, and shows BsaA forms intermolecular isopeptide bonds to enhance biofilm fiber strength.

This study evaluates the effect of quantified cranial osteopathic manipulation on Alzheimer's disease rat models, finding no significant behavioral changes in young rats but altered spatial memory in aged transgenic rats.

This study identifies a new family of LDTs in C. difficile that catalyze 3-3 peptidoglycan crosslinking, essential for viability and distinct from previously known YkuD domain LDTs.

The paper develops genetically encoded auxin biosensors in yeast to measure auxin concentration and improve understanding of auxin perception and production across organisms.