MYC/MAX balance dictates cell progenitor fate by altering the HOX program in the Drosophila eye
Sara Monticelli, Giorgio Milazzo, Suleman Khan Zadran, Martina Santulli, Nicola Balboni, Silvia Strocchi, Ettore De Giorgio, Pieter Mestdagh, Angela Giangrande, Roberto Bernardoni, Giovanni Perini
This study shows that altering the MYC/MAX ratio in Drosophila eye progenitors changes cell fate by rewiring HOX gene expression and reprogramming progenitor identity.
Frontiers in Cell and Developmental Biology · Oct 26, 2026Peer-reviewedDevelopmental Biology