Jasper Anckaert

The paper identifies NESPR, an adrenergic-specific lncRNA, as a regulator of neuroblastoma cell identity that prevents cell death by attenuating stress.

HTSplotter automates data processing, analysis, and visualization for in vitro perturbation screens, supporting multiple experimental types and time-course data.

The paper benchmarks 16 circRNA detection tools across three human cell types, finding large differences in sensitivity but consistent precision, and recommends tool combinations for improved detection.

This paper introduces a 3'-end capture sequencing method for targeted gene expression profiling, achieving 100-fold enrichment of target genes with shallow sequencing.

The paper evaluates RNA purification kits and blood collection tubes for exRNA quality, finding that preservation tubes and purification methods significantly affect RNA stability, sensitivity, and reproducibility.

The paper creates a comprehensive atlas of RNA transcriptomes across 20 human biofluids, revealing significant differences in RNA concentration and composition, and validates potential biomarkers in disease cohorts.

This study benchmarks single cell RNA-seq technologies to assess their ability to detect transcriptional changes in NGP neuroblastoma cells after nutlin-3 treatment, finding heterogeneity in response not captured by bulk RNA-seq.

The paper evaluates the SMARTer Stranded Total RNA-Seq method's performance in quantifying total RNA from various human biofluids and extracellular vesicles, finding it accurate, precise, and capable of detecting thousands of genes.

The paper presents a comprehensive human transcriptome atlas with single-nucleotide resolution, identifying thousands of novel RNA species and regulatory interactions.

The paper introduces a novel single cell strand-specific total RNA sequencing method that overcomes limitations of existing techniques and detects more genes, including non-polyadenylated ones.

The paper introduces Zipper plot, a tool to visualize transcriptional activity around TSSs using RNA-seq and other genomic data.