Author

James T. Walsh

Washington University in St. LouisORCID 0000-0002-0170-5796Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrea C. SantefordiD· 1 shared Brian S. SohniD· 1 shared Charles W. PfeiferiD· 1 shared Daniel Du· 1 shared Jason J. ColasantiiD· 1 shared Jiayi Li· 1 shared Joseph B. LiniD· 1 shared Keitaro HaseiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Andrea C. SantefordORCID

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1 paper

Recent·Most cited

Macrophage immunosenescence prolongs intraocular inflammation in aged mice via impaired induction of regulatory T cells

Taku Yamamoto, Keitaro Hase, Joseph B. Lin, Shinobu Yamaguchi, Norihiko Misawa, Jiayi Li, Kenta Kato, Ryo Terao, Brian S. Sohn, Daniel Du, Mitsukuni Yoshida, Charles W. Pfeifer, Tae Jun Lee, Jason J. Colasanti, Andrea C. Santeford, , Rajendra S. Apte

This study shows that aging impairs macrophage-induced regulatory T cells in mice, leading to chronic uveitis by linking immunosenescence to persistent inflammation.

bioRxiv · Jan 20, 2026 · PreprintImmunology