Author

Christopher John Ong

University of British ColumbiaORCID 0000-0002-0175-8724Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Colin C. CollinsiD· 2 shared Dong LiniD· 2 shared Junru CheniD· 2 shared Martin Edwin GleaveiD· 2 shared Mingchen Shi· 2 shared Rebecca WuiD· 2 shared Xinyao Pang· 2 shared Yen‐Yi LiniD· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Colin C. CollinsORCID

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2 papers

Recent·Most cited

Longitudinal single-cell profiling links RUNX1T1 to lineage transition and maintenance in treatment-induced neuroendocrine prostate cancer

Yuchao Ni, Mingchen Shi, Dong Lin, Yen‐Yi Lin, Hui Xue, Xin Dong, Liangliang Liu, Funda Sar, Rebecca Wu, Tunç Morova, Anne M. Haegert, Robert H. Bell, Xinyao Pang, Adam Classen, Wei Dong, , Yuzhuo Z. Wang

This study uses longitudinal single-cell RNA sequencing to identify RUNX1T1 as a key regulator in the transition and maintenance of treatment-induced neuroendocrine prostate cancer.

bioRxiv · May 14, 2025 · PreprintCancer Biology

Deciphering the Transcription Factor Landscape in Neuroendocrine Prostate Cancer Progression: A Novel Approach to Understand NE Transdifferentiation

Yu Wang, Hui Xue, Xiaohui Zhu, Dong Lin, Zheng Chen, Xin Dong, Junru Chen, Mingchen Shi, Yuchao Ni, Jonathan Cao, Rebecca Wu, Connie Kang, Xinyao Pang, Francesco Crea, Yen‐Yi Lin, , Yuzhuo Z. Wang

This study identifies lineage-specific transcription factor profiles in prostate cancer progression, revealing dynamic shifts during NE transdifferentiation and proposing a three-phase model.

Advanced Science · Mar 17, 2025Peer-reviewedCancer Biology