Anne M. Haegert

Longitudinal single-cell RNA sequencing of a neuroendocrine transdifferentiation model reveals transcriptional reprogramming in treatment-induced neuroendocrine prostate cancer

This study uses longitudinal scRNA-seq to track neuroendocrine transdifferentiation in a prostate cancer model, identifying transcriptional changes and key regulators during treatment-induced NEPC progression.

Longitudinal single-cell profiling links RUNX1T1 to lineage transition and maintenance in treatment-induced neuroendocrine prostate cancer

This study uses longitudinal single-cell RNA sequencing to identify RUNX1T1 as a key regulator in the transition and maintenance of treatment-induced neuroendocrine prostate cancer.

Identifying Rare Germline Variants Associated with Metastatic Prostate Cancer Through an Extreme Phenotype Study

This study identifies rare germline variants associated with metastatic prostate cancer using an extreme phenotype cohort and validates their functional impact.

AR-V7 condensates drive androgen-independent transcription in castration resistant prostate cancer

This study shows AR-V7 forms condensates independently of androgens and AR-FL in CRPC, driving oncogenic transcription through both condensate-dependent and -independent mechanisms.