Author

Chikim Nguyen

Institute for Atomic and Molecular PhysicsORCID 0000-0002-0176-3136Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Kristina A. GanzingeriD· 2 shared Ricardo A. FernandesiD· 2 shared Sander J. TansiD· 2 shared A. Christina HeroveniD· 1 shared Anne Walters· 1 shared Gerard Castro-LinaresiD· 1 shared Lucrezia C D E Gatti· 1 shared Mai Tuyet VuongiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiophysics

Kristina A. GanzingerORCID

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2 papers

Recent·Most cited

Low CAR affinity enhances T-cell synapse dynamics and activation

Chikim Nguyen, Gerard Castro-Linares, Lucrezia C D E Gatti, Zsolt Sebestyén, Ricardo A. Fernandes, Sander J. Tans, Megan V. Farrell, Kristina A. Ganzinger

This study shows that low CAR affinity improves T-cell synapse dynamics and activation by promoting receptor turnover and signaling.

bioRxiv · Oct 12, 2026 · PreprintBiophysics

Bilayer acoustic force spectroscopy (BAFS) for quantifying receptor-antigen binding strength in immune synapses

Nebojsa Jukic, Tom M. J. Evers, Anne Walters, Chikim Nguyen, Mai Tuyet Vuong, A. Christina Heroven, Ricardo A. Fernandes, Sander J. Tans, Kristina A. Ganzinger

This paper introduces BAFS, a method to measure receptor-antigen binding strength in immune synapses with high precision and reduced non-specific binding.

bioRxiv · Mar 25, 2026 · PreprintBiophysics