Author

John I. Goutsias

Johns Hopkins UniversityORCID 0000-0002-0192-3857Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:long-read sequencing· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Jordi AbanteiD· 2 shared Albert A. LeeiD· 1 shared Ali Sobhi Afshar· 1 shared Allister Suarez· 1 shared Andrew P. FeinbergiD· 1 shared Brian HuangiD· 1 shared Diana Bobb· 1 shared Elmer RhoiD· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBioinformatics

Jordi AbanteORCID

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintFeb 22, 2021

Estimating DNA methylation potential energy landscapes from nanopore sequencing data

Jordi Abante, Sandeep Kambhampati, Andrew P. Feinberg, John I. Goutsias

The paper introduces a method to model DNA methylation landscapes from nanopore sequencing data, accounting for sequencer noise and demonstrating its potential through simulations.

DOI 10.1101/2021.02.22.431480

long-read sequencingstatistical model

BioinformaticsbioRxivPreprintOct 17, 2020

CpelTdm.jl: a Julia package for targeted differential DNA methylation analysis

Jordi Abante, John I. Goutsias

CpelTdm.jl is a Julia package that performs targeted differential DNA methylation analysis, detecting differences in methylation stochasticity between groups of samples.

1 citation

DNA methylationstatistical model

Synthetic BiologyNature MaterialsPeer-reviewedNov 6, 2017

Intracellular production of hydrogels and synthetic RNA granules by multivalent enhancers

Hideki Nakamura, Albert A. Lee, Ali Sobhi Afshar…·Takanari Inoue

The paper develops iPOLYMER, a method to induce protein-based hydrogels in living cells, mimicking RNA granules by sequestering polyadenine-containing nucleotides.

133 citations

experimental assay