Sandeep Kambhampati

Vermeer generates synthetic microscopy images of protein localization using protein sequences and cell morphology, outperforming previous methods in quality and flexibility.

TissueMosaic performs cross-sample differential analysis of spatial transcriptomics data using self-supervised representation learning to improve detection of genes associated with tissue structure changes.

Slide-tags enables spatial localization of single nuclei for multi-modal spatial genomics, achieving high-resolution mapping and multiomic profiling in various tissues.

The paper identifies universal gene pathways and regulators involved in organ maturation across four mouse tissues.

This study identifies PGC1/PPAR signaling and its regulators Yap1 and SF3B2 as key drivers of cardiomyocyte maturation through single-cell transcriptomic analysis across neonatal to adult hearts.

The paper introduces a method to model DNA methylation landscapes from nanopore sequencing data, accounting for sequencer noise and demonstrating its potential through simulations.