Author

Albert A. Lee

Johns Hopkins UniversityORCID 0000-0002-7238-1274Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

Ali Sobhi Afshar· 1 shared Allister Suarez· 1 shared Brian HuangiD· 1 shared Daniel Alexander MokhtariiD· 1 shared Daniel HerschlagiD· 1 shared Diana Bobb· 1 shared Elmer RhoiD· 1 shared Emily D. EganiD· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperSynthetic Biology

Ali Sobhi Afshar

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BiochemistrybioRxivPreprintApr 2, 2026

High-throughput biochemical phenotyping of SHP2 variants reveals the molecular basis of diseases and allosteric drug inhibition

Albert A. Lee, Daniel Alexander Mokhtari, Emily D. Egan…·Polly Morrell Fordyce

This study uses high-throughput biochemical assays to analyze SHP2 variants, revealing that dysregulated autoinhibition drives disease and that allosteric inhibitors stabilize a partially active conformation.

1 citation

proteomicsexperimental assay

𝕏 PostBluesky

Synthetic BiologyNature MaterialsPeer-reviewedNov 6, 2017

Intracellular production of hydrogels and synthetic RNA granules by multivalent enhancers

Hideki Nakamura, Albert A. Lee, Ali Sobhi Afshar…·Takanari Inoue

The paper develops iPOLYMER, a method to induce protein-based hydrogels in living cells, mimicking RNA granules by sequestering polyadenine-containing nucleotides.

133 citations

experimental assay

𝕏 PostBluesky