Author

Anne E.J. Hillen

Emma KinderziekenhuisORCID 0000-0002-0200-3745Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Marjo S. van der KnaapiD· 2 shared Vivi Majella HeineiD· 2 shared Gerbren Jacobs· 1 shared Kyoko WatanabeiD· 1 shared Lisa Gasparotto· 1 shared Paulien Cornelissen‐Steijger· 1 shared Prisca S. LeferinkiD· 1 shared Robbert Zalm· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 30 mutual co-author links

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2 shared papersNeuroscience

Marjo S. van der KnaapORCID

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2 papers

Recent·Most cited

Gene supplementation in Vanishing White Matter mice ameliorates the disease

Anne E.J. Hillen, Robbert Zalm, Marjo S. van der Knaap, Vivi Majella Heine

This study shows that gene supplementation in astrocytes of Vanishing White Matter mice improves motor skills and CNS pathology without side effects.

bioRxiv · Dec 9, 2025 · PreprintNeuroscience

Human and mouse iPSC-derived astrocyte subtypes reveal vulnerability in Vanishing White Matter

Prisca S. Leferink, Stephanie Dooves, Anne E.J. Hillen, Kyoko Watanabe, Gerbren Jacobs, Lisa Gasparotto, Paulien Cornelissen‐Steijger, Marjo S. van der Knaap, Vivi Majella Heine

This study generates human and mouse iPSC-derived grey and white matter-like astrocytes, revealing subtype-specific defects in Vanishing White Matter disease.

bioRxiv · Jan 17, 2019 · PreprintNeuroscience