Stephanie Dooves

This study uses human oligodendrocyte spheroids to model leukodystrophies and identifies disease-specific transcriptional changes and lineage-specific vulnerabilities.

This study investigates how 4H leukodystrophy mutations affect cortical interneuron development using induced pluripotent stem cells and finds reduced GABAergic synapses and altered interneuron markers.

This study generates human and mouse iPSC-derived grey and white matter-like astrocytes, revealing subtype-specific defects in Vanishing White Matter disease.