Author

Jenna Persson

Karolinska InstitutetORCID 0000-0002-0208-8080Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Bernhard SchmiereriD· 1 shared Emma Maria HaapaniemiiD· 1 shared Jussi TaipaleiD· 1 shared Sandeep Kumar BotlaiD· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperGenomics

Bernhard SchmiererORCID

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1 paper

Recent·Most cited

Inhibition of p53 improves CRISPR/Cas-mediated precision genome editing

Emma Maria Haapaniemi, Sandeep Kumar Botla, Jenna Persson, Bernhard Schmierer, Jussi Taipale

Cas9-induced double-strand breaks trigger p53/p21/RB1-dependent G1 arrest in RPE-1 cells; transient p53 inhibition via MDM2 markedly raises homologous recombination precision editing efficiency.

Nature Medicine · Jun 8, 2018Peer-reviewedGenomics✦ In-depth digest