GenomicsbioRxivPreprint
Transcriptomic and phenotypic characterization of Alzheimer's disease risk genes in neurons and astrocytes highlights shared and cell type specific cellular mechanisms
Caia S. Dominicus, Diego Peretti, Geraldine Rodschinka…·Andrew Roger Bassett
The paper uses single-cell transcriptomics and phenotypic analysis of gene knockouts in hiPSC-derived neurons and astrocytes to identify cell-type specific and shared mechanisms of Alzheimer's disease risk genes.