Diego Peretti

The paper uses single-cell transcriptomics and phenotypic analysis of gene knockouts in hiPSC-derived neurons and astrocytes to identify cell-type specific and shared mechanisms of Alzheimer's disease risk genes.

This study examines the role of perineuronal nets (PNNs) in memory and learning after synaptic withdrawal induced by an hibernation-like state, finding that PNN absence affects synaptic restoration but not long-term memory storage.

Inducing cold shock protein RBM3 by modulating its alternative splicing at normothermia is neuroprotective in vivo.