Author

Daniel X. Le

GenentechORCID 0000-0002-0220-6366Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Ana Xavier‐MagalhãesiD· 2 shared Jessica M. Lund· 2 shared Jonathan HooveriD· 2 shared Julia LauiD· 2 shared Marco Claudio De SimoneiD· 2 shared Minyi ShiiD· 2 shared Zora D. ModrusaniD· 2 shared Ahmet A. Kurdoglu· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Ana Xavier‐MagalhãesORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintFeb 20, 2025

Promoter-centric gene regulation in drug-resistant cancer

Vasumathi Kameswaran, Sayantanee Paul, Daniel X. Le…·Bence Dániel

This study shows that mesothelioma cells develop drug resistance by reverting to a promoter-centric gene regulation mechanism when treated with a TEAD inhibitor.

2 citations

humanChIP-seq

Molecular BiologybioRxivPreprintJun 18, 2024

Comparative Analysis of Commercial Single-Cell RNA Sequencing Technologies

Marco Claudio De Simone, Jonathan Hoover, Julia Lau…·Spyros Darmanis

This study compares ten commercial scRNA-seq technologies using PBMCs, finding the 10x Genomics kit offers superior performance and the Becton Dickinson kit provides cost-effective performance per cell.

20 citations

humanscRNA-seq