Author

Jonathan Hoover

GenentechORCID 0000-0002-2893-4425Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:benchmarking· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Ana Xavier‐MagalhãesiD· 3 shared Jessica M. Lund· 3 shared Zora D. ModrusaniD· 3 shared Daniel X. LeiD· 2 shared Julia LauiD· 2 shared Marco Claudio De SimoneiD· 2 shared Minyi ShiiD· 2 shared Ahmet A. Kurdoglu· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersNeuroscience

Ana Xavier‐MagalhãesORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintMay 19, 2026

Direct RNA Sequencing reveals epitranscriptomic regulation of brain cells and Alzheimer's Disease pathology

Ashley Byrne, Jonathan Hoover, Jessica M. Lund…·Daniel Le

This study uses direct RNA sequencing to analyze epitranscriptomic changes in brain cells, revealing m6A modification patterns linked to Alzheimer's disease progression.

DOI 10.64898/2026.05.18.724443

humanlong-read sequencing

𝕏 PostBluesky

Cancer BiologybioRxivPreprintFeb 20, 2025

Promoter-centric gene regulation in drug-resistant cancer

Vasumathi Kameswaran, Sayantanee Paul, Daniel X. Le…·Bence Dániel

This study shows that mesothelioma cells develop drug resistance by reverting to a promoter-centric gene regulation mechanism when treated with a TEAD inhibitor.

2 citations

humanChIP-seq

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Molecular BiologybioRxivPreprintJun 18, 2024

Comparative Analysis of Commercial Single-Cell RNA Sequencing Technologies

Marco Claudio De Simone, Jonathan Hoover, Julia Lau…·Spyros Darmanis

This study compares ten commercial scRNA-seq technologies using PBMCs, finding the 10x Genomics kit offers superior performance and the Becton Dickinson kit provides cost-effective performance per cell.

20 citations

humanscRNA-seq

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