Induction of expansion of ex vivo NK cells using a new feeder cell built in Brazil. An extended flow cytometry evaluation of K562.mbIL21.4BBL
Caroline Mitiká Watanabe, C. Ishihama Suzuki, Alessandro Marins-Dos-Santos, Thiago Pinheiro Arrais Aloia, Grace E. Lee, David N. Wald, Oswaldo Keith Okamoto, Julia T. Cottas de Azevedo, Juliana Aparecida Preto de Godoy, Fabio P S Santos, Ricardo Weinlich, Lucila Nassif Kerbauy, José Mauro Kutner, Raquel M. Alves‐Paiva, Nelson Hamerschlak
This paper develops a Brazilian feeder cell, K562.Clone1, which expands NK cells ex vivo more than 100-fold while preserving their antitumor activity.
Transplantation and Cellular Therapy · Jul 8, 2024Peer-reviewedCancer Biology