Author

Jérôme Clain

InsermORCID 0000-0002-0232-5058Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Evolutionary Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:plant (other)· 2 Assay:protein structure· 2 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:protein structure prediction· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Romain CoppéeiD· 3 shared Anna Cosson· 1 shared Antoine Bridier‐NahmiasiD· 1 shared Atikatou MamaiD· 1 shared Audrey Sabbagh· 1 shared Claire KamaliddiniD· 1 shared Daniel C. Jeffares· 1 shared Franck LetourneuriD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersBioinformatics

Romain CoppéeORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

CONSTRUCT: an algorithmic tool for identifying functional or structurally important regions in protein tertiary structure

Lucas Chivot, Noé Mathieux, Anna Cosson, Antoine Bridier‐Nahmias, Loïc Favennec, Jean‐Christophe Gelly, Jérôme Clain, Romain Coppée

CONSTRUCT identifies functional or structurally important regions in protein tertiary structure by weighting substitution rates with neighboring sites' rates.

Bioinformatics · Mar 29, 2025Peer-reviewedBioinformatics

5WBF: A low-cost and straightforward whole blood filtration method suitable for whole-genome sequencing of Plasmodium falciparum clinical isolates

Romain Coppée, Atikatou Mama, Véronique Sarrasin, Claire Kamaliddin, Lucie Adoux, Lawrence Palazzo, Nicaise Tuikue Ndam, Franck Letourneur, Frédéric Ariey, Sandrine Houzé, Jérôme Clain

This paper introduces a low-cost filtration method (5WBF) to enrich Plasmodium falciparum DNA from whole blood, enabling effective whole-genome sequencing even at low parasitemias.

Malaria Journal · Feb 16, 2022Peer-reviewedGenomics

Structural evolutionary analysis predicts functional sites in the artemisinin resistance malaria protein K13

Romain Coppée, Daniel C. Jeffares, Audrey Sabbagh, Jérôme Clain

The paper identifies conserved regions in the K13 protein of Plasmodium falciparum as potential functional sites using evolutionary and structural analysis.

bioRxiv · Jun 21, 2018 · PreprintEvolutionary Biology