Romain Coppée

This study identifies skeletocutin E as a dual-stage antimalarial compound that inhibits Plasmodium falciparum pyruvate kinase II, showing efficacy against both blood and liver stages of the parasite.

CONSTRUCT identifies functional or structurally important regions in protein tertiary structure by weighting substitution rates with neighboring sites' rates.

This paper introduces a low-cost filtration method (5WBF) to enrich Plasmodium falciparum DNA from whole blood, enabling effective whole-genome sequencing even at low parasitemias.

The paper identifies conserved regions in the K13 protein of Plasmodium falciparum as potential functional sites using evolutionary and structural analysis.