Author

Claudio Umberto Köser

University of CambridgeORCID 0000-0002-0232-846XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Andrea SpitaleriiD· 1 shared Daniela María CirilloiD· 1 shared Ivan BarilariD· 1 shared Luca FreschiiD· 1 shared Maha Reda FarhatiD· 1 shared Paolo MiottoiD· 1 shared Roger VargasiD· 1 shared Sabira TahseeniD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperGenomics

Andrea SpitaleriORCID

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1 paper

Recent·Most cited

The role of epistasis in amikacin, kanamycin, bedaquiline, and clofazimine resistance in Mycobacterium tuberculosis complex

Roger Vargas, Luca Freschi, Andrea Spitaleri, Sabira Tahseen, Ivan Barilar, Stefan Niemann, Paolo Miotto, Daniela María Cirillo, Claudio Umberto Köser, Maha Reda Farhat

The paper demonstrates epistatic interactions in Mycobacterium tuberculosis complex that can reverse antibiotic resistance, specifically showing that eis promoter mutations cannot confer resistance if paired with LoF mutations in the eis coding region.

Antimicrobial Agents and Chemotherapy · Aug 30, 2021Peer-reviewedGenomics