Paolo Miotto

This study shows how different Mycobacterium tuberculosis lineages interact with macrophage phenotypes to affect phagosomal acidification, highlighting the complexity of host-pathogen interactions in tuberculosis.

This study quantifies antibiotic resistance in tuberculosis using genomic data and MIC measurements to identify genetic determinants of resistance and hypersensitivity across multiple drugs.

The paper demonstrates epistatic interactions in Mycobacterium tuberculosis complex that can reverse antibiotic resistance, specifically showing that eis promoter mutations cannot confer resistance if paired with LoF mutations in the eis coding region.