Author

Marcelo Carlos Sousa

University of Colorado BoulderORCID 0000-0002-0242-3619Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 2 Assay:protein structure· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alexandre M. PlastowiD· 1 shared Brandon DzubaiD· 1 shared Emad TajkhorshidiD· 1 shared Katherine E. DaProniD· 1 shared Marc-André LeBlanciD· 1 shared Morgan R. FinkiD· 1 shared Thomas T. PerkinsiD· 1 shared Whitney N. BergmaniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

Alexandre M. PlastowORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintJan 1, 2026

A Type III secretion system effector evolved to be mechanically labile and initiate unfolding from the N-terminus.

Katherine E. DaPron, Alexandre M. Plastow, Morgan R. Fink…·Marcelo Carlos Sousa

This paper shows that effector proteins are mechanically labile, unfolding from the N-terminus, which facilitates their secretion via the Type III secretion system.

2 citations

protein structurebiophysical modeling

𝕏 PostBluesky

BiochemistryProceedings of the National Academy of SciencesPeer-reviewedDec 24, 2025

A fluorescent reporter and single-turnover kinetics reveal new insight into BAM complex function

Whitney N. Bergman, Marcelo Carlos Sousa

The paper develops a fluorescent reporter to study BAM complex function in vitro, revealing that POTRA domains 1-3 are not critical for catalysis but may support structural interactions.

1 citation

bacteria (other)protein structure

𝕏 PostBluesky