Author

Lai Jiang

Jewish General HospitalORCID 0000-0002-0244-4620Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Research Focus:GWAS / association mapping· 2 Assay:GWAS summary statistics· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:database / resource· 1 Research Focus:fine-mapping· 1

Frequent Co-Authors

Celia M.T. GreenwoodiD· 2 shared John Brent RichardsiD· 2 shared and for the Alzheimer’s Disease Neuroimaging Initiative· 1 shared Andréa Lessa BenedetiD· 1 shared Antonio CiampiiD· 1 shared Christian BenneriD· 1 shared Dongkeun JangiD· 1 shared Eric B. FaumaniD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBioinformatics

Celia M.T. GreenwoodORCID

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2 papers

Recent·Most cited

BioinformaticsHuman GeneticsPeer-reviewedFeb 11, 2022

An Effector Index to Predict Causal Genes at GWAS Loci

Vincenzo Forgetta, Lai Jiang, Nicholas A. Vulpescu…·John Brent Richards

The paper introduces the Effector Index, an algorithm to predict causal genes at GWAS loci using genomic features, achieving 85% AUC in type 2 diabetes validation.

75 citationstop 1%

humanGWAS summary statistics

GeneticsGenetic EpidemiologyPeer-reviewedJan 12, 2019

Constrained Instruments and their Application to Mendelian Randomization with Pleiotropy

Lai Jiang, Karim Oualkacha, Vanessa Didelez…·and for the Alzheimer’s Disease Neuroimaging Initiative

This paper introduces Constrained Instrumental Variable (CIV) methods to improve Mendelian randomization by handling pleiotropy, showing better performance in simulations and application to ADNI data.

23 citations

humanGWAS summary statistics