Author

Iliya M. Lefterov

University of PittsburghORCID 0000-0002-0249-0280Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 4 Research Focus:differential expression· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Nicholas Francis FitziD· 4 shared Radosveta P. KoldamovaiD· 4 shared A. N. M. Mamun-Or-RashidiD· 1 shared Amanda E. Moore· 1 shared C. J. CavanaughiD· 1 shared Carolina Saibro GirardiiD· 1 shared Daniel C. LeeiD· 1 shared Daniel Pens GelainiD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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4 shared papersNeuroscience

Nicholas Francis FitzORCID

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4 papers

Recent·Most cited

NeuroscienceInternational Journal of Molecular SciencesPeer-reviewedJun 3, 2026

Integration of transcriptional signatures from brain tissue and plasma extracellular vesicles of a preclinical tauopathy mouse model

Tanzima Tarannum Lucy, A. N. M. Mamun-Or-Rashid, Daniel C. Lee…·Nicholas Francis Fitz

The paper integrates transcriptomic data from brain tissue and plasma extracellular vesicles in a tauopathy mouse model, identifying shared non-coding RNA signatures that reflect central nervous system changes.

DOI 10.3390/ijms27115050

mousebulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintMar 17, 2026

A novel technique for monitoring Alzheimer's disease associated changes in brain-derived extracellular vesicle cargos in mouse models

Nicholas Francis Fitz, Shahnur Alam, Mary Ann Ostach…·Radosveta P. Koldamova

This study develops an in vivo method to collect brain-derived extracellular vesicles from mouse models and identifies unique small ncRNA signatures associated with Alzheimer's disease.

1 citation

mouseexperimental assay

𝕏 PostBluesky

NeuroscienceInternational Journal of Molecular SciencesPeer-reviewedMar 6, 2026

Brain single-cell transcriptional responses to bexarotene-activated RXR in Alzheimer's disease model

Carolina Saibro Girardi, Lu Yi, Nicholas Francis Fitz…·Radosveta P. Koldamova

This study investigates the cell-specific transcriptional responses to bexarotene in Alzheimer's disease mouse models, revealing APOE's role in RXR-mediated neuroprotection.

2 citations

mousescRNA-seq

𝕏 PostBluesky

GenomicsInternational Journal of Molecular SciencesPeer-reviewedAug 14, 2025

Transcriptomic Response to Neuromuscular Electrical Stimulation in Muscle, Brain and Plasma EVs in WT and Klotho-deficient Mice

C. J. Cavanaugh, Amanda E. Moore, Nicholas Francis Fitz…·Radosveta P. Koldamova

The paper evaluates transcriptomic changes in muscle, brain, and plasma EVs of WT and Klotho-deficient mice after NMES, showing genotype-specific responses in metabolic and immune pathways.

1 citation

mousebulk RNA-seq

𝕏 PostBluesky