Julien Messéant

This study identifies GDF5 as a protective factor in ALS by restoring SMAD signaling and preserving motor unit integrity through gene delivery in a mouse model.

This study shows that SMN insufficiency in muscle stem cells leads to long-term motor neuron loss through non-cell autonomous mechanisms in SMA.

This study identifies Vangl2 as a regulator of MuSK signaling in neuromuscular synapse formation, showing its role in AChR accumulation and NMJ stability.