Androgen receptor imprints satellite cells stemness and preserves their reservoir for lifelong regeneration and optimal repair
Joe G. Rizk, Kamar C. Ghaibour, Sirine Souali‐Crespo, Emilia Calvano, Aurore Bilger, Hugues Jacobs, Nadia Messaddeq, Qingshuang Cai, Erwan Grandgirard, Rajesh Sahu, Arnaud Ferry, Valentin Fourcade, Joffrey Zoll, Gianni Zanardelli, Nacho Molina, , Delphine Duteil
This study shows androgen receptor signaling maintains skeletal muscle stem cell quiescence and regenerative capacity, and its loss leads to premature activation and stem cell depletion.
Science Advances · Sep 9, 2026Peer-reviewedDevelopmental Biology