Non-Canonical Cytochrome P450 Enzymes in Nature
Andy K. L. Nguy, Kendra A. Ireland, Chase M. Kayrouz, Juan Carlos Caceres, Jonathan Z. Huang, Vanessa Y. Ying, Joanna Afokai Quaye, Brandon L. Greene, Katherine M. Davis, Mohammad R. Seyedsayamdost
The paper identifies and characterizes non-canonical CYPs lacking the conserved cysteine ligand, revealing new ligands like serine and selenocysteine in microbial genomes.
Nature Chemical Biology · Jun 22, 2026Peer-reviewedBiochemistry