Cancer BiologyCancer DiscoveryPeer-reviewed
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Single-cell spatial atlas of high-grade serous ovarian cancer unveils MHC class II as a key driver of spatial tumor ecosystems and clinical outcomes
Fernando Pérez‐Villatoro, Aleksandra Shabanova, Lilian van Wagensveld…·Anniina Färkkilä
Cyclic immunofluorescence of 265 high-grade serous ovarian carcinomas and random-forest feature ranking identify cancer-cell MHC-II as an adjusted predictor of longer survival marking immune-activated tumor-stroma hotspots.