Author
Sanford Burnham Prebys Medical Discovery InstituteORCID 0000-0002-0289-5712Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Adarsh Rajesh, Aaron P. Havas, Rouven Arnold…·Peter D. Adams
This study shows that targeting CCND1-CDK6 reduces DNA damage, inflammation, and age-related decline in mice by suppressing SASP and ISG expression.
Zong Ming Chua, Hiroshi Tanaka, Adrianna Abele…·Peter D. Adams
This study shows that a H2A.Z mutant reduces the senescence-associated secretory phenotype in human fibroblasts without affecting cell cycle genes.
Rouven Arnold, Marcos G. Teneche, Xue Lei…·Peter D. Adams
This study shows that HIRA-mediated H3.3 deposition maintains hepatocyte identity during aging, and its loss leads to metabolic dysfunction and fibrosis, which can be partially reversed by tissue regeneration.