Author

Alan P. R. Lorenzetti

Lieber Institute for Brain DevelopmentORCID 0000-0002-0291-248XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Adrián López García de LomanaiD· 1 shared Amilton de Lima BarbosaiD· 1 shared Apuã C.M. PaquolaiD· 1 shared Arthur Sant’Anna FeltriniD· 1 shared Bailey Spiegelberg· 1 shared Bruno Henrique Silva AraújoiD· 1 shared Daniel R. WeinbergeriD· 1 shared Ethan Tietze· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperSystems Biology

Adrián López García de LomanaORCID

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2 papers

Recent·Most cited

Systems BiologymSystemsPeer-reviewedMar 13, 2023

A genome-scale atlas reveals complex interplay of transcription and translation in an archaeon

Alan P. R. Lorenzetti, Ulrike Kusebauch, Livia Soares Zaramela…·Nitin S. Baliga

This study integrates omics data to reveal post-transcriptional regulation mechanisms in Halobacterium salinarum NRC-1, showing 54% of genes are regulated by multiple mechanisms and 7% show conditional regulation.

12 citations

DNA methylationproteomics

Developmental BiologybioRxivPreprintAug 29, 2020

A single cell trajectory of human archetypal pluripotent stem cell differentiation to trophoblast stem cells reveals induction of endogenous BMP5/7 and GATA3 without transitioning through a naive state

Ethan Tietze, Amilton de Lima Barbosa, Bruno Henrique Silva Araújo…·Jennifer A. Erwin

This paper shows that primed human pluripotent stem cells can differentiate to trophoblast stem cells without becoming naive, using specific signaling conditions and revealing a transcriptional network involving BMP5/7 and GATA3.

DOI 10.1101/2020.08.29.273425