Author

Amilton de Lima Barbosa

Johns Hopkins UniversityORCID 0000-0002-3261-984XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Apuã C.M. PaquolaiD· 2 shared Arthur Sant’Anna FeltriniD· 2 shared Bruno Henrique Silva AraújoiD· 2 shared Daniel R. WeinbergeriD· 2 shared Jennifer A. ErwiniD· 2 shared Joel E. KleinmaniD· 2 shared Kynon JM BenjaminiD· 2 shared Thomas M. HydeiD· 2 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Apuã C.M. PaquolaORCID

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2 papers

Recent·Most cited

Ventral forebrain organoids derived from individuals with schizophrenia recapitulate perturbed striatal gene expression dynamics of the donor's brains

Tomoyo Sawada, Amilton de Lima Barbosa, Bruno Henrique Silva Araújo, Alejandra E. McCord, Laura D’Ignazio, Kynon JM Benjamin, Arthur Sant’Anna Feltrin, Ria Arora, Anna C. Brandtjen, Joel E. Kleinman, Thomas M. Hyde, Daniel R. Weinberger, Apuã C.M. Paquola, Jennifer A. Erwin

The paper uses ventral forebrain organoids from schizophrenia patients and controls to show accelerated maturation of inhibitory neurons and shared gene expression patterns with postmortem brain tissue.

bioRxiv · May 26, 2022 · PreprintNeuroscience

A single cell trajectory of human archetypal pluripotent stem cell differentiation to trophoblast stem cells reveals induction of endogenous BMP5/7 and GATA3 without transitioning through a naive state

Ethan Tietze, Amilton de Lima Barbosa, Bruno Henrique Silva Araújo, Veronica Luiza Vale Euclydes, Hyeon Jin Cho, Yong Kyu Lee, Arthur Sant’Anna Feltrin, Bailey Spiegelberg, Alan P. R. Lorenzetti, Joyce van de Leemput, Pasquale Di Carlo, Tomoyo Sawada, Gianluca Ursini, Kynon JM Benjamin, Helena Brentani, , Jennifer A. Erwin

This paper shows that primed human pluripotent stem cells can differentiate to trophoblast stem cells without becoming naive, using specific signaling conditions and revealing a transcriptional network involving BMP5/7 and GATA3.

bioRxiv · Aug 29, 2020 · PreprintDevelopmental Biology