Spatial Transcriptomics Identifies Muscle Inflammation Susceptibility as a Distinct Periarticular Skeletal Muscle Phenotype in End-Stage Knee Osteoarthritis
Francesco Pinto Boeno, Zachary Graham, Qi Su…·Marcas M. Bamman
Author
Johnson & Johnson (United States)ORCID 0000-0002-0296-4984Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Francesco Pinto Boeno, Zachary Graham, Qi Su…·Marcas M. Bamman
Jillian M. Jespersen, Lia Avanesyan, Jean Publicover…·Jody L. Baron
The paper identifies shared mechanisms of HBsAg seroclearance using a mouse model and longitudinal PBMCs from CHB patients, showing CD4+ T cell activation is essential for clinical cure.
Michael J. Stec, Zachary Graham, Qi Su…·Marcas M. Bamman
This study examines how combined aerobic and resistance exercise training affects the spatial transcriptome of skeletal muscle in young adults, identifying fiber type-specific gene expression changes and shifts in interstitial cell populations.