Marcas M. Bamman

Molecular Transducers of Physical Activity Consortium (MoTrPAC): Initial Insights into the Dynamic Human Responses to Exercise

The paper presents initial findings from the MoTrPAC consortium, showing that acute and chronic exercise induce distinct physiological and molecular responses, with chronic training improving key health metrics.

Spatial Transcriptomics Identifies Muscle Inflammation Susceptibility as a Distinct Periarticular Skeletal Muscle Phenotype in End-Stage Knee Osteoarthritis

Serum metabolomics signatures after an acute bout of combined traditional or high-intensity tactical training in young males and females

This study compares serum metabolomics responses to traditional combined exercise and high-intensity tactical training in young adults, finding similar patterns but greater magnitude changes with traditional exercise.

The Long Non-coding RNA Landscape of Endurance Exercise Training

This study identifies tissue-specific lncRNA responses to endurance exercise in rats, revealing sex differences and potential therapeutic implications.

Multi-omic identification of key transcriptional regulatory programs during endurance exercise training in rats

The paper identifies tissue-specific transcriptional regulatory programs in rats undergoing endurance exercise training by integrating chromatin accessibility, DNA methylation, and gene expression data.

Combined aerobic and resistance exercise training alters the spatial transcriptome of skeletal muscle in young adults

This study examines how combined aerobic and resistance exercise training affects the spatial transcriptome of skeletal muscle in young adults, identifying fiber type-specific gene expression changes and shifts in interstitial cell populations.

DNA Methylation Dynamics of Dose-dependent Acute Exercise, Training Adaptation, and Detraining

This study examines DNA methylation changes in blood and muscle across different training programs and timepoints, identifying DMRs linked to exercise adaptation, sex, and physiological functions.

Effects of leg immobilization and recovery resistance training on skeletal muscle-molecular markers in previously resistance trained versus untrained adults

This study examines how resistance training status affects muscle size and molecular markers during leg immobilization and recovery training in young adults.

Sexual dimorphism and the multi-omic response to exercise training in rat subcutaneous white adipose tissue

This study examines how endurance exercise training affects rat subcutaneous white adipose tissue, revealing sex-specific molecular responses and differences in adiposity and metabolism.

Temporal dynamics of the multi-omic response to endurance exercise training across tissues

This study profiles multi-omic changes in multiple tissues of rats during endurance exercise training, identifying molecular adaptations and sex-specific responses across time.

Dynamic Transcriptomic Network Responses to Divergent Acute Exercise Challenges in Young Adults

The paper compares transcriptomic responses in skeletal muscle and extracellular vesicles after traditional and high-intensity exercise in young adults, finding more consistent gene responses to traditional exercise and unique microRNA responses to high-intensity training.

Novel Genetic Loci Associated with Osteoarthritis in Multi-Ancestry Analyses in 484,374 Participants from MVP and the UK Biobank.

The paper identifies 10 novel genetic loci associated with osteoarthritis in multi-ancestry analyses of 484,374 participants from MVP and UK Biobank, with some regions robust across populations.

miR-486 is an epigenetic modulator of Duchenne muscular dystrophy pathologies

The paper shows miR-486 is reduced in DMD muscles and its loss causes muscle and cardiac defects, identifying it as a driver of disease and a potential biomarker.