Chuan Cao

This paper introduces GO-CRE, a method for designing cell-type-specific cis-regulatory elements by reconstructing sequence-grammar trajectories and using reinforcement learning with predictor guidance.

The paper introduces {micro}Protein, a framework combining deep learning and reinforcement learning to predict and discover high-gain protein mutants using single mutation data.

This study identifies LmGypsy, a retrotransposon in locusts, as a mediator of antiviral immunity that synergizes with RNAi and cGAS-like receptors to defend against viral infection.