Exosomes promote axon outgrowth by engaging the Wnt-Planar Cell Polarity pathway
Samar Ahmad, Melanie Pye, Masahiro Narimatsu, Siyuan Song, Tania Y. Christova, Jeffrey L. Wrana, Liliana Attisano
This study shows fibroblast-derived exosomes promote axon outgrowth in neurons via the Wnt-PCP pathway, while neuron- or astrocyte-derived exosomes do not or inhibit this process.
bioRxiv · Oct 28, 2023 · PreprintNeuroscience