Liliana Attisano

The paper introduces VIVOS, a 3D human vascular platform that links intraluminal flow to endothelial state transitions and vessel remodeling through YAP/TAZ-Apelin signaling.

This study identifies three GFAP+ astrocyte subtypes in human cerebral organoids, showing greater morphological complexity than mouse astrocytes but not fully recapitulating adult human complexity.

This study uses iPSC-derived cerebral organoids to show mitochondrial and inflammatory dysfunctions in bipolar disorder and tests potential therapeutic interventions.

This study examines how a bioactive flavonoid extract suppresses NLRP3 inflammasome activation and inflammation in both 2D and 3D lung models.

This paper identifies 5342191 as a broad-spectrum antiviral that inhibits HIV-1, adenovirus, coronavirus, and influenza by altering viral RNA accumulation and structural protein expression.

This study shows fibroblast-derived exosomes promote axon outgrowth in neurons via the Wnt-PCP pathway, while neuron- or astrocyte-derived exosomes do not or inhibit this process.

This study shows that LTK and ALK regulate neuronal polarity and migration by modulating IGF1R activity, leading to behavioral abnormalities when disrupted.

The paper shows Neurog2 and Ascl1 genes regulate cortical progenitor differentiation and folding through Notch signaling in lissencephalic brains.

The paper develops cerebral organoids from iPSCs derived from PBMCs to study mitochondrial health across stages and shows preserved mitochondrial function and treatment responses.

This study develops a robust method to produce uniform human cerebral organoids with consistent morphology and cell type composition, achieving an 80% success rate.