Author

Amy E. Schade

Brigham and Women's HospitalORCID 0000-0002-0342-8251Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Alexandra IndegliaiD· 1 shared Franziska Michor AiD· 1 shared Karen M. CichowskiiD· 1 shared Simone BrunoiD· 1 shared Sophia Lichterfeld· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperCancer Biology

Alexandra IndegliaORCID

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1 paper

Recent·Most cited

A mechanistic digital twin model for epigenetic therapy optimization in triple-negative breast cancer

Simone Bruno, Alexandra Indeglia, Sophia Lichterfeld, Amy E. Schade, Karen M. Cichowski, Franziska Michor A

This paper develops a digital twin model to optimize epigenetic therapies in triple-negative breast cancer by simulating treatment responses and identifying effective drug combinations.

bioRxiv · Sep 16, 2026 · PreprintCancer Biology