GenomicsThe American Journal of Human GeneticsPeer-reviewed
Massively parallel characterization of CYP2C9 variant enzyme activity and abundance
Clara J. Amorosi, Melissa A. Chiasson, Matthew G. McDonald…·Maitreya J. Dunham
The paper characterizes CYP2C9 variant enzyme activity and abundance using Click-seq and VAMP-seq, finding that two-thirds of variants show decreased activity and abundance explains half the functional variation.
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