Yves Le Loir

Human milk bacteria assembled into functionally distinct synthetic communities in infant formula differently affect intestinal physiology and microbiota in neonatal mini-piglets

This study evaluates how two synthetic communities of human milk bacteria, with different immunomodulatory properties, affect gut microbiota and physiology in neonatal piglets.

Staphylococcus aureus derived extracellular vesicles trigger multiple inflammatory pathways in host cells and deliver their RNA cargo following their internalization and lysis within late endosomes

New insights into the cultivability of human milk microbiota from ingestion to digestion and implications for its immunomodulatory properties

This study examines the cultivability and immunomodulatory properties of human milk microbiota before and after digestion, finding reduced diversity and loss of immunomodulatory effects in most strains.