Svetlana V Chabelskaya

Cross-regulatory sRNA networks shape adaptive stress responses in Staphylococcus aureus: RsaC and RsaOI regulate galactose metabolism and cell wall homeostasis

This study identifies regulatory interactions between sRNAs and transcription factors in S. aureus, showing their roles in stress responses and virulence.

Ribo-seq reveals IsrR-mediated translational repression of SAOUHSC_02924 (gabT) during iron limitation in Staphylococcus aureus

The paper uses Ribo-seq to show IsrR represses gabT translation during iron limitation in S. aureus, preventing TCA cycle precursor accumulation and metabolic imbalance.

Staphylococcus aureus derived extracellular vesicles trigger multiple inflammatory pathways in host cells and deliver their RNA cargo following their internalization and lysis within late endosomes

sRNA-mediated crosstalk between cell wall stress and galactose metabolism in Staphylococcus aureus

This study identifies RsaOI, an sRNA in S. aureus, that links cell wall stress responses to galactose metabolism by regulating the tagatose pathway.

Staphylococcal aconitase expression during iron deficiency is controlled by an sRNA-driven feedforward loop and moonlighting activity

The paper shows that IsrR, an sRNA, controls aconitase expression in S. aureus during iron deficiency through a feedforward loop and aconitase's moonlighting activity regulates central metabolism.