Author

Ulrike Holzgrabe

University of WürzburgORCID 0000-0002-0364-7278Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Bettina Friedl· 1 shared Carsten HoffmanniD· 1 shared Edith Kaczmarek· 1 shared F. SörgeliD· 1 shared Franziska RichteriD· 1 shared Friederike WunschiD· 1 shared Gerhard WolberiD· 1 shared Jenny C. FiloriD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperSystems Biology

Bettina Friedl

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2 papers

Recent·Most cited

BioinformaticsJournal of Chemical Information and ModelingPeer-reviewedMar 16, 2026

Dynamic pharmacophores unveil binding mode ensembles for classical partial agonists at the M2 receptor

Friederike Wunsch, Michael Kauk, Jenny C. Filor…·Marcel Bermúdez

This study uses dynamic pharmacophores to analyze binding mode ensembles of M2 receptor partial agonists and shows correlations between ligand efficacy and spatial distribution of lipophilic contacts.

2 citationstop 4%

experimental assayprotein structure prediction

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Systems BiologybioRxivPreprintSep 16, 2020

Tissue Level Profiling of SARS-CoV-2 antivirals in mice to predict their effects: comparing Remdesivir's active metabolite GS-441 524 vs. the clinically failed Hydroxychloroquine

Oliver Scherf‐Clavel, Edith Kaczmarek, Martina Kinzig…·F. Sörgel

This study compares the tissue distribution and pharmacokinetics of GS-441 524 and hydroxychloroquine in mice to assess their potential antiviral efficacy against SARS-CoV-2.

1 citation

mousestatistical model

𝕏 PostBluesky