Author

Oliver Scherf‐Clavel

University of WürzburgORCID 0000-0002-1967-9231Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Neuroscience· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

Alex M. DickensiD· 1 shared Anna-Mari Haapanen-SaaristoiD· 1 shared Bettina Friedl· 1 shared Edith Kaczmarek· 1 shared F. SörgeliD· 1 shared Franziska RichteriD· 1 shared Heike BähreiD· 1 shared Ilia EvstafeviD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperCancer Biology

Alex M. DickensORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Pharmacokinetics and efficacy of tank-water administered BRAF-inhibitor dabrafenib in a zebrafish model of BRAF-mutant melanoma

Jenna Villman, Nikol Dibus, Jonas Huhn, Anna-Mari Haapanen-Saaristo, Ilia Evstafev, Alex M. Dickens, Oliver Scherf‐Clavel, Ilkka Paatero, Kari J. Kurppa

This study evaluates the pharmacokinetics and efficacy of tank-water administered dabrafenib in zebrafish with BRAF-mutant melanoma, showing rapid absorption, short half-life, and effective treatment with minimal toxicity.

bioRxiv · Oct 12, 2025 · PreprintCancer Biology

Octopamine drives honeybee thermogenesis

Sinan Kaya-Zeeb, Lorenz Engelmayer, Mara Straßburger, Jasmin Bayer, Heike Bähre, Roland Seifert, Oliver Scherf‐Clavel, Markus Thamm

This study identifies octopamine as essential for honeybee thermogenesis, showing it induces hypothermia when depleted and restores thermogenesis when administered.

eLife · Feb 16, 2022Peer-reviewedNeuroscience

Tissue Level Profiling of SARS-CoV-2 antivirals in mice to predict their effects: comparing Remdesivir's active metabolite GS-441 524 vs. the clinically failed Hydroxychloroquine

Oliver Scherf‐Clavel, Edith Kaczmarek, Martina Kinzig, Bettina Friedl, Malte Feja, Rainer Höhl, Roland Nau, Ulrike Holzgrabe, Manuela Gernert, Franziska Richter, F. Sörgel

This study compares the tissue distribution and pharmacokinetics of GS-441 524 and hydroxychloroquine in mice to assess their potential antiviral efficacy against SARS-CoV-2.

bioRxiv · Sep 16, 2020 · PreprintSystems Biology