Impairing NK-mediated immune rejection through NKG2DL editing to improve CAR-T cell persistence
Hui Shi, Yi Wang, Xin Tang, Guangna Liu
This study shows that editing ULBP ligands reduces NK cell rejection of UCAR-T cells, improving their persistence and antitumor efficacy.
bioRxiv · Apr 9, 2026 · PreprintImmunology