Author

Sayoko E. Moroi

The Ohio State UniversityORCID 0000-0002-0418-0657Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Bin GuaniD· 2 shared Gabrielle M. RozumekiD· 2 shared Lev PrasoviD· 2 shared Robert B. HufnageliD· 2 shared Amelia NaikiD· 1 shared Bridget Blevins· 1 shared Catherine A. ToweriD· 1 shared Douglas Ford HannumiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenetic & Genomic Medicine

Bin GuanORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Pathogenic MYRF ICA Domain Variant is Aberrantly Trafficked in the RPE and Results in Isolated Nanophthalmos

Gabrielle M Rozumek, Rachel S. Lim, William Presley, Bridget Blevins, Bin Guan, John Y. S. Han, Ehsan Ullah, Amelia Naik, Tara E. Hahn, Rodrigo Young, Sayoko E. Moroi, Robert B. Hufnagel, Jason M. L. Miller, Lev Prasov

This study identifies a pathogenic MYRF variant causing isolated nanophthalmos by showing it is cleavage deficient, mislocalized, and reduces transcriptional activity with SOX10.

medRxiv · Nov 9, 2026 · PreprintGenetic & Genomic Medicine

Splicing variants in MYRF cause partial loss of function in the retinal pigment epithelium

Gabrielle M. Rozumek, Michelle Lynn Brinkmeier, Bin Guan, Su Qing Wang, Catherine A. Tower, Nina T. Yang, Rachel Lim, Lijin Dong, Douglas Ford Hannum, Sayoko Eileen Moroi, Julia E. Richards, Robert B. Hufnagel, Lev Prasov

The paper identifies a hypomorphic MYRF variant causing partial loss of function in the RPE, with two novel splicing variants linked to isolated nanophthalmos.

bioRxiv · Apr 21, 2025 · PreprintGenetics