Catherine A. Tower

This study shows that protamine PTMs create heterogeneous chromatin states in sperm, affecting fertility and chromatin integrity.

The paper shows maternal CENP-C restores centromere symmetry in zygotes by asymmetrically recruiting to paternal centromeres, ensuring proper chromosome segregation.

The paper identifies a hypomorphic MYRF variant causing partial loss of function in the RPE, with two novel splicing variants linked to isolated nanophthalmos.

This study uses deep learning to predict protein-protein interactions in bacterial pathogens, identifying new complexes involving essential genes and virulence factors, with half of tested predictions validated.

The paper tracks CENP-A dynamics in mouse gametes and embryos, showing sex-specific differences in centromere maintenance and equalization during early development.