Lian Zhang

BioMod introduces biological modules as intermediate units for single-cell foundation modeling, achieving state-of-the-art performance in cell-type annotation and drug-response prediction.

The paper evaluates whether label-free morphology can replace targeted cellular measurements by analyzing paired phase-reporter data across gene knockouts and screens.

This paper shows that INPP5E regulates phospholipid distribution in cilia of mouse olfactory neurons, affecting odor response adaptation but not sensitivity.