Author

Iván Dotú

Universitat Pompeu FabraORCID 0000-0002-0438-9557Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:CUT&Tag· 1 Research Focus:database / resource· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Eduardo EyrasiD· 2 shared Adrià CaballéiD· 1 shared Amadís Pagès· 1 shared Ángel R. NebredaiD· 1 shared Annarita SibilioiD· 1 shared Benjamin ColemaniD· 1 shared Chiara Lara Castellazzi· 1 shared Clara SuñeriD· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBioinformatics

Eduardo EyrasORCID

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3 papers

Recent·Most cited

A dynamic equilibrium between TTP and CPEB4 controls mRNA stability and inflammation resolution

Clara Suñer, Annarita Sibilio, Judit Martín, Chiara Lara Castellazzi, Óscar Reina, Iván Dotú, Adrià Caballé, Elisa I. Rivas, Vittorio Calderone, Juana Díez, Ángel R. Nebreda, Raúl Méndez

The paper shows that CPEB4 and TTP regulate mRNA stability during inflammation resolution through competing polyadenylation and deadenylation, shaping the inflammatory response.

eLife · Apr 20, 2022Peer-reviewedMolecular Biology

SARNAclust: Semi-Automatic Detection Of RNA Protein Binding Motifs From Immunoprecipitation Data

Iván Dotú, Scott I. Adamson, Benjamin Coleman, Cyril Fournier, Emma Ricart Altimiras, Eduardo Eyras, Jeffrey H. Chuang

SARNAclust identifies RNA motifs from immunoprecipitation data by combining structure/sequence analysis, revealing known and novel motifs including a new ILF3 motif similar to hnRNPC.

PLoS Computational Biology · Mar 29, 2018Peer-reviewedBioinformatics

The discovery potential of RNA processing profiles

Amadís Pagès, Iván Dotú, Joan Pallarès-Albanell, Eulàlia Martı́, Roderic Guigó, Eduardo Eyras

The paper introduces SeRPeNT, a method to discover and characterize small non-coding RNAs using RNA processing profiles, identifying new sncRNAs and differential processing patterns.

Nucleic Acids Research · Nov 10, 2017Peer-reviewedGenomics